Howe's side travel to Stamford Bridge on Sunday to face Chelsea, who will be playing their second game since the Russian billionaire's UK assets were frozen.
Newcastle defender Kieran Trippier faces a race to return before the end of the season after having surgery on his broken foot.
Guardiola has tested negative for COVID-19, British media reported, after an inconclusive test earlier on Friday prompted the club to cancel his pre-match news conference.
The Egyptian was not happy with Klopp's decision and the coach was asked for an explanation after the match.
Howe will be in the Newcastle dugout for the first time at Arsenal on Saturday after returning a negative test for coronavirus.
Pulisic suffered an ankle injury while playing for the United States during the international break last month.
Liverpool continue to adopt a cautious approach with the Spaniard, who suffered a knee injury in the Merseyside derby in October.
Bruce said on Friday that they are still without some of the players who tested positive for COVID-19.
Newcastle United said they have signed defender Danny Rose from Tottenham Hotspur on loan until the end of the season.
Chelsea kept up their 100 percent start to the Premier League season by snatching a 2-1 win at a stubborn Newcastle United on Sunday, grabbing victory thanks to a late own goal by DeAndre Yedlin.
Chelsea were denied a place in next season’s Champions League when they were well beaten 3-0 at Newcastle as Liverpool easily beat Brighton.
Huddersfield Town's survival in the Premier League means that not one of the 16 teams promoted in England's top five divisions last season have been relegated 12 months later
Newcastle United's on-loan striker Islam Slimani will miss the rest of the Premier League season after being handed a three-match ban for violent conduct by the English Football Association (FA)
Newcastle United virtually guaranteed their Premier League safety as they came from a goal down to beat Arsenal 2-1 at a spring-like St James' Park on Sunday.
Southampton's refusal to sell defender Virgil van Dijk in the close season had disrupted their Premier League campaign which ultimately led to manager Mauricio Pellegrino being sacked.
Matt Ritchie lifted the gloom on Tyneside with the winner in Newcastle United's crucial 1-0 victory over Manchester United
Manchester United have to continue fighting for the Premier League title regardless of the 13-point gap to leaders Manchester City, defender Antonio Valencia said.
Batshuayi took advantage of a rare start to score twice as Chelsea eased past Newcastle 3-0 at Stamford Bridge on Sunday to reach the fifth round of the FA Cup.
Manchester City's relentless assault on English football's record books continued on Wednesday.
Conte has warned that playmaker Hazard is yet to hit his peak at the Premier League club and backed the Belgian to become one of the best players in the world.