The Bavarians put down a marker at the start of the campaign as they look to land an 11th consecutive league crown.
Regardless of the jersey that Mane will wear next season, he hopes to celebrate the prestigious title on Saturday night in Paris.
The 30-year-old has scored 20 goals in 44 appearances for Liverpool this season, including six in his last seven, as the club seek to secure an unprecedented quadruple.
Liverpool did enough to build themselves a solid lead for Tuesday's return game in Spain where they will be confident of finishing off the job.
Egypt secured a 1-0 win on Friday night, which gives the Pharaohs a slight advantage in the second leg.
The two teams will face off on Tuesday night in Senegal to decide who will pick one of Africa's five tickets to the 2022 FIFA World Cup.
The game ended in a 1-0 win for the Pharaohs and everything will be decided in the second leg in Senegal next Tuesday.
The Pharaohs hope for a second consecutive participation and a fourth presence in the prestigious event after 1934, 1990 and 2018.
Al Ahly’s Mohamed Magdy Afsha was named in the squad after being ruled out of the Pharaohs’ list that participated in the Africa Cup of Nations in Cameroon.
Mohamed Salah and Sadio Mane scored twice each as Liverpool crushed Leeds United 6-0.
Mohamed Salah, Sadio Mane and Luis Diaz will feature in Liverpool’s attack as the hero of Milan’s match, Roberto Firmino, is out of the game for injury.
Klopp has a full squad at his disposal with Henderson back from injury, and forwards Salah and Sadio Mane making their first starts since returning from the AFCON in Liverpool's win over Burnley.
The Egyptian winger is running down the last 18 months of his contract and the club owners failed to convince him till now to pen a new contract.
Sarr could yet be able to play for Senegal in the Africa Cup of Nations finals after a 'positive development' in medical checkups on his injured knee, the Senegal Football Federation said on Wednesday.
Mane said that the Egyptian winger is currently the best player in the world, ahead of the duo’s participation in the upcoming Africa Cup of Nations in Cameroon.
Aliou Cisse has selected 27 players for the tournament in Cameroon, including captain Kalidou Koulibaly and Ismaila Sarr, who have both been out with injury.
FIFA regulations state clubs must release players for AFCON by Dec. 27, which is 13 days before the tournament starts.
Klopp said he has spoken to Mane about how to deal with such situations.
The Egyptian is now leading the top scorers list in the league with 7 goals. He also comes second in the list of the best assist providers with four assists.
Liverpool celebrated the return of a full house to Anfield by extending their 100 percent start to the Premier League season as goals from Diogo Jota and Sadio Mane saw off Burnley.