City beat Liverpool to the title by a point last season, and in the 2018-19 campaign.
Manchester City must pick themselves off the floor for the visit of Newcastle in the Premier League.
De Bruyne has been in scintillating form for City this season, bagging 15 goals and 12 assists in 40 games in all competitions.
With only one point separating City and Liverpool, Klopp praised his team's improvement and said both clubs have pushed each other to get better.
That was the ideal preparation for the seismic showdown with City, who also face Liverpool in the FA Cup semi-finals at Wembley on April 16.
Liverpool boss Jurgen Klopp and Manchester City manager Pep Guardiola were outspoken critics of the previous refusal to adopt the change.
Guardiola's side will look to reach the FA Cup semi-finals on Sunday when they travel to Southampton for their last eight tie.
The Russian billionaire was one of seven oligarchs targeted Thursday by the UK government following Russia's invasion of Ukraine.
All the hard work for the English champions was done in the Portuguese capital three weeks ago.
The 63-year-old German is due to start a two-year consultancy role after the season finishes.
City host Tottenham on Saturday looking to hand the visitors a fourth successive league defeat.
Manchester United moved into the top four of the Premier League with a last second goal from Marcus Rashford earning them a 1-0 win over West Ham United at Old Trafford.
Foden stroked home in the 16th minute from Kevin de Bruyne's pass and it proved sufficient to seal a 10th successive league win for Pep Guardiola's relentless champions.
Ralf Rangnick and his City counterpart Pep Guardiola have both urged the Premier League to increase the number of substitutions from three to five.
Guardiola believes Leicester will pose a formidable challenge to his Premier League leaders despite a slump in form.
Top flight leagues in Europe adopted the rule to increase the number of substitutions per game to five to ease the workload on players.
Guardiola has tested negative for COVID-19, British media reported, after an inconclusive test earlier on Friday prompted the club to cancel his pre-match news conference.
De Bruyne says he is not yet back to his best after testing positive for the coronavirus last month.
De Bruyne has tested positive for COVID-19 on international duty with Belgium, manager Pep Guardiola said on Friday.
Guardiola and Klopp were also dugout rivals in Germany's Bundesliga between 2013 and 2015 as the Spaniard's Bayern Munich dominated at the expense of Klopp's Borussia Dortmund.