French Prime Minister Jean Castex submitted his resignation Monday, setting the stage for a cabinet reshuffle as Macron embarks on his second term.

Borne spoke soon after her appointment, noting the emotions she felt at being selected for the highest office a woman has ever held in French political leadership.

“I would like to dedicate this nomination to all the little girls by telling them ‘Go after your dreams!’ Nothing should stop the fight for the place of women in our society,” she said.

Macron and Borne are expected to appoint a new French government in the coming days.